People determine the age and health of someone they meet within 10 seconds. Skin is a telltale sign people use to gauge overall health and age. Medical research now reveals why dehydroepiandrosterone (DHEA) drives this.
After age 25, sex hormones begin a gradual decline. By age 35, both men and women begin to notice the effects of declining hormones in many different ways. Quality of sleep at night declines, as does energy, mood, muscle tone, sex drive and more. Declining hormone levels are strongly associated with many important health measures, such a cardiovascular health, bone strength, mental sharpness and more. These are all signs of gradual hormone decline that we call aging. These unfortunate declines may be slowed or avoided by maintaining youthful DHEA levels, a crucial hormone precursor. Using DHEA as a properly made DHEA supplement cream called Twist 25 is key.
Skin or the dermis is the largest organ of the human body. It’s an external indicator of age and health. Medical research reveals why DHEA is so important to improve the health and appearance of skin. How does DHEA cream do so much good for skin? There are many science-based reasons:
- DHEA is a base for “sebum.” Sebum is also known as skin oil. Sebum helps to keep the skin supple. It also has antimicrobial properties that keep irritations at bay. The end result is brighter skin that's more hydrated and healthier-looking.1
- In a 2000 clinical study, researchers determined that DHEA helps the body produce collagen. Collagen is a protein important in connective tissue that gradually deteriorates as we age. As skin is depleted of collagen, it loses its elasticity and starts to look thin or “papery,” appearing to sag and wrinkle. At the same time this is occurring, collagenase enzymes speed up the process of collagen decline.2
- DHEA not only helps the body produce collagen, but also helps to inhibit the production of collagenase, which breaks down collagen. With regular daily use of Twist 25 DHEA cream, users maintain strong healthy connective tissues, supporting healthy collagen in the dermis and yielding healthier, more youthful-looking skin.2
- In addition, a 2008 Canadian study reinforced the findings of the 2000 study. In the 2008 study, researchers noted that DHEA cream appears to help the body "switch on" special genes that are responsible for collagen production.3
- DHEA also reduces the number of keratinocytes. Keratinocytes make skin rougher and cause formation of calluses. So, by using DHEA cream daily you can effectively keep skin smooth and soft.4
- DHEA cream reduces the risk of both chemical and UV carcinogens; and DHEA also fades keratoses or “age spots” or “liver spots.” 5,6

Twist 25® DHEA Cream is a pharmaceutical-grade skin cream made with bioidentical DHEA, in an absorbable coconut oil base. Maintain young-looking, soft, beautiful skin while maintaining your hormones, collagen and sebum with Twist 25 DHEA cream.
Feel your best. Look your best.
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